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Pancreatic ELASTASE 1 Elisa serum
    Tests for the quantification of human pancreatic elastase 1,Two ELISA test kits (based on monoclonal antibodies) are available for the determination of pancreatic elastase 1. The stool test quantifies E1 in stool, allowing the diagnosis or exclusion of pancreatic exocrine insufficiency, which can be caused by chronic pancreatitis, cystic fibrosis, pancreatic tumor, cholelithiasis or diabetes mellitus for example.The serum test quantifies E1 in serum, allowing the diagnosis or exclusion of an acute pancreatitis or an inflammatory episode of chronic pancreatitis or ERCP- or gallstone-induced pancreatitis.

Tests for the quantification of human pancreatic elastase 1

Two ELISA test kits (based on monoclonal antibodies) are available for the determination of pancreatic elastase 1. The stool test quantifies E1 in stool, allowing the diagnosis or exclusion of pancreatic exocrine insufficiency, which can be caused by chronic pancreatitis, cystic fibrosis, pancreatic tumor, cholelithiasis or diabetes mellitus for example.
The serum test quantifies E1 in serum, allowing the diagnosis or exclusion of an acute pancreatitis or an inflammatory episode of chronic pancreatitis or ERCP- or gallstone-induced pancreatitis.

Serum Test

Human pancreatic elastase 1 is synthesized from the acinar cells of the pancreas. During an inflammatory episode of the pancreas, E1 is released into the blood circulation. Thus the quantification of pancreatic elastase 1 in the serum allows diagnosis or exclusion of acute pancreatitis.

ScheBo®   Pancreatic Elastase 1™ Serum Test

Diagnosis/Exclusion of Acute Pancreatitis                      

Main indications and diagnosis:

  • Diagnosis/Exclusion of Acute Pancreatitis
  • Diagnosis of ERCP- or gallstone-induced pancreatitis
  • Follow-up study of acute pancreatitis

Advantages

E1 is absolutely pancreas-specific. Like other pancreatic enzymes, E1 is released into the blood circulation during an inflammatory episode. Due to its longer half-life, compared to amylase and lipase, its concentration remains elevated longer, and enables detection of an acute pancreatitis even three of four days after onset of the disease. In contrast to amylase and lipase, the serum E1 concentration is only marginally increased in patients with renal insufficiency.

» The test
Further indications, advantages, reference concentration, specificity and sensitivity, method of detection, sample material, short protocol

» References/literature download
Please find here selected literature as download. The complete list of references is to be found on „References/literature fax request“.

» References/literature fax request
Here you can download a pdf-file with a list of references/literature. If you you are interested in any of these publications please fill in the form, fax it to us and we will send it to you free of charge.